8:00 am
Registration & Continental Breakfast
8:50 am
Welcoming Remarks
Gerry Boss, MD - UC San Diego School of Medicine
SESSION I - Metabolism and Cellular Adaptation
J. Silvio Gutkind, PhD - UC San Diego School of Medicine (Moderator)
9:00 am
The Expanding Lexicon of Metabolic Signaling
Jared P. Rutter, PhD - University of Utah School of Medicine
9:30 am
Q&A Discussion
9:40 am
Failing Up: How Mitochondrial Dysfunction Becomes a Metastatic Advantage
Kevin Tharp, PhD - Sanford Burnham Prebys Medical Discovery Institute
10:10 am
Q&A Discussion
10:20 am
How Nutrients Leave Their Mark: Metabolic Crosstalk with the Epigenome in Cancer and Immunity
Kathryn E. Wellen, PhD - University of Pennsylvania Perelman School of Medicine
10:50 am
Q&A Discussion
11:00 am
Break
SESSION II - Immunometabolism and Translational Therapeutics
Brooke Emerling, PhD - Sanford Burnham Prebys Medical Discovery Institute (Moderator)
11:15 am
Good to Great and Built to Last: Enabling Immune Cells to Fight Cancer
Jonathan Powell, MD, PhD - Calico Labs
11:45 am
Q&A Discussion
11:55 am
Interrogating and Targeting Stromal Cell Plasticity in Pancreatic Cancer
Ellen Langer, PhD - Oregon Health & Science University
12:25 pm
Q&A Discussion
12:35 pm
Lunch on own (please see registration for a list of suggestions)
2:00 pm
Cholesterol Homeostasis as a Vulnerability in Pancreatic Cancer
David Tuveson, MD, PhD - Cold Springs Harbor Laboratory Cancer Center
2:30 pm
Q&A Discussion
SESSION III - Autophagy, Stress Responses, and Tumor Survival
Christina Towers, PhD - Salk Institute for Biological Studies (Moderator)
2:40 pm
Organelle-Driven Metabolic Adaptation in Pancreatic Cancer Progression
Rushika M. Perera, PhD - UCSF Helen Diller Family Comprehensive Cancer Center
3:10 pm
Q&A Discussion
3:20 pm
Break
3:35 pm
Understanding the Roles of Antioxidants in Health and Disease
Isaac S. Harris, PhD - The Harris Lab at the University of Rochester Medical Center
4:05 pm
Q&A Discussion
4:15 pm
Targeting Autophagy in Cancer: Trials and Tribulations
Ravi K. Amaravadi, MD - University of Pennsylvania Perelman School of Medicine
4:45 pm
Q&A Discussion
4:55 pm
Closing Remarks
Brooke Emerling, PhD - Sanford Burnham Prebys Medical Discovery Institute
5:00 pm
Final Adjournment