7:30 am
Registration/Check-in
8:50 am
Welcoming Remarks
Gerry Boss, MD, University of California San Diego
SESSION I
Diana Hargreaves, PhD - Salk Institute (Moderator)
9:00 am
Reversal of Aging by Low Frequency Ultrasound in Vitro and in Vivo
Michael Sheetz, PhD - University of Texas Medical Branch, Galveston
9:30 am
Discussion
9:40 am
Biomechanical Hallmarks and Vulnerabilities of Metastatic Cancer Cells
Victoria Sanz-Moreno, PhD - Institute of Cancer Research
10:10 am
Discussion
10:20 am
Mechano-Metabolic Programming and the Immune Evasive Glycocalyx
Kevin Tharp, PhD - Sanford-Burnham Presby Medical Research Institute
10:50 am
Discussion
11:00 am
Break
SESSION II
Cosimo Commisso, PhD - Sanford Burnham Prebys (Moderator)
11:15 am
Nuclear Mechanobiology of Cancer Cells – The Effects of Cells Squeezing Through Tight spaces and other Lessons Learned
Jan Lammerding, PhD - Cornell
11:45 am
Discussion
11:55 am
Losses of Nuclear Integrity Drive the PARP Inhibitor Response in Homologous Recombination - Deficient Tumor Cells
Megan King, PhD - Yale University
12:25 pm
Discussion
12:35 pm
Lunch
2:00 pm
Mechanisms of Cancer Invasion and Immune Cell Migration in the Tumor Microenvironment
Ovijit Chaudhuri, PhD - Stanford University
2:30 pm
Discussion
SESSION III
Jing Yang, PhD - University of California San Diego (Moderator)
2:40 pm
Interplay Between Tissue Tension, Inflammation and Tumor Initiation and Progression
Valerie Weaver, PhD - UC San Francisco
3:10 pm
Discussion
3:20 pm
Break
3:35 pm
Engineering Self-Propelled Tumor-Infiltrating CAR T Cells Using Synthetic Velocity Receptors
Denis Wirtz, PhD - John's Hopkins
4:05 pm
Discussion
4:15 pm
The Mechanometabolism of Cell Migration
Cynthia A. Reinhart-King, PhD - Vanderbilt University
4:45 pm
Discussion
4:55 pm
Closing Remarks
Jing Yang, PhD - University of California San Diego